Bone Marrow Is a Reservoir of Repopulating Mesangial Cells during Glomerular Remodeling
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چکیده
منابع مشابه
Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling.
The renal glomerulus, whose cellular components are developmentally derived from the mesenchyme, plays a pivotal role in filtratating plasma. Irretrievable changes of glomerular components are responsible for the initiation and progression of impaired renal function. Recently, it has been shown that functional stem cells exist in the bone marrow of adult bodies and that they can reconstitute da...
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Glomerular mesangial cell (MC)-derived IL-1 may be an important factor in the development of the hypercellularity and sclerosis characteristic of many forms of glomerulonephritis. To define the regulation of IL-I synthesis by human MC, Northern blot analyses were performed using specific probes for monocytic IL-1 a and 8 mRNA. Proliferating MC expressed mRNA for both IL-1 a and ft, whereas nonp...
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of bone marrow-derived cells to differentiate to glomerular mesangial cells. Extraglomerular origin of the mesangial cells after injury. marrow is a reservoir of repopulating mesangial cells during glomerular remodelling. A, Plati AR et al. Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors. Bone marrow transplantation attenuates murine IgA nephropathy: role of ...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2001
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v12122625